Subclinical hypothyroidism (SH) is particularly frequent in individuals with Down syndrome (DS). Despite the amount of evidence suggesting SH is associated with psychopathological symptoms and sleep problems in general population, poor is known about the emotional and behavioral features associated with SH in children with DS. Emotional and Behavioral Features Associated with Subclinical Hypothyroidism in Children and Adolescents with Down Syndrome Source: Fucà et al.