The Down Syndrome Clinical Trials Network (DS-CTN) is a collaboration of multiple sites throughout the continental United States designed as a future framework to conduct large-scale, multi-site trials under the supervision of experienced clinicians who are experts at providing medical care for individuals with Down syndrome.
At present, the DS-CTN is focused on its founding project: the Longitudinal Investigation for the Enhancement of Down Syndrome Research (LIFE-DSR) study. LIFE-DSR is a longitudinal cohort study of 270 adults with Down syndrome, their medical histories, and blood samples, as well as biomarker and neuropsychological testing data. LIFE-DSR is actively recruiting new participants and currently undergoing expansion. It has already yielded some preliminary data.